News & Events

IRB approval to open the trial in Georgetown University for the treatment of mtKRAS tumors from GI track

29 Nov|

Following FDA approval to open our trial at Georgetown University in Washington DC, we received final IRB approval to open the trial in Georgetown University for the treatment of mtKRAS tumors from GI track

New Nerofe Formulation for treatment of Stage 4 squamous cell lung cancer

29 Nov|

Using a new formulation of Nerofe, treating a patient with Stage 4 squamous cell lung cancer (positive for ST2), caused the complete disappearance of some tumors and a decrease in the size of other tumors. Increase in hepatic function.

New Nerofe Formulation for treatment of adenocarcinoma in the anus with metastasis in the peritoneum

29 Nov|

Using a new formulation of Nerofe on a patient (positive for ST2) with adenocarcinoma in the anus and two metastasis in the peritoneum caused the complete disappearance of tumors.

ISK Ltd received FDA approval to start phase1/1b trial for treatment of GI tract mtKRAS tumors patients at Georgetown University at Washington DC

23 Oct|

ISK Ltd received FDA approval to start phase1/1b trial for treatment of GI tract mtKRAS tumors patients at Georgetown University at Washington DC

Phase II update – A second patient (92 years old) had a strong reduction in blasts in the bone marrow

01 Jun|

No side effects were recorded

Update from AML human trial in Miami

04 May|

Who is entitled to enroll in the trial:
AML /Hi-Risk MDS patients with:

8 weeks of life expectancy.
clinically deteriorating.
have no more available treatments.

In cohort 1 (dose=6mg/m^2) three patients were enrolled.

The first patient was alive with this dose for 5 months.
The second patient was alive with this dose for 1.5 months.
The third

Georgetown University at Washington DC has signed a contract with ISK to run a clinical trial with patients with mtKRAS tumors

17 Feb|

The prestigious medical center Georgetown University at Washington DC has sign a contract with ISK to run a clinical trial with patients with mtKRAS pancreas and colon cancers.

PHASE 1B/2A Clinical trial started

13 Apr|

The Nerofe Phase 1B/2A trial with high risk MDS and AML patients is taking place at the University of Miami Sylvester Comprehensive Cancer Center.

ISK received the FDA’s approval to start Phase 1b/2a with AML patients

09 Jan|

Cooperation with Harvard Medical School (MGH)

27 Oct|

ISK has signed an agreement for cooperation with Harvard Medical School for drug development to treat neurodegenerative diseases