News

Second FDA approved clinical trial in patients with pancreatic cancer and metastatic colorectal18/12/2022

ISK is excited to report the official opening of its second FDA approved clinical trial in the US in patients with pancreatic cancer and metastatic colorectal cancer at Georgetown University in Washington, D.C.

18 Dec|

IRB approval to open the trial in Georgetown University for the treatment of mtKRAS tumors from GI track29/11/2022

Following FDA approval to open our trial at Georgetown University in Washington DC, we received final IRB approval to open the trial in Georgetown University for the treatment of mtKRAS tumors from GI track

29 Nov|

New Nerofe Formulation for treatment of Stage 4 squamous cell lung cancer

Using a new formulation of Nerofe, treating a patient with Stage 4 squamous cell lung cancer (positive for ST2), caused the complete disappearance of some tumors and a decrease in the size of other tumors. Increase in hepatic function.

29 Nov|

New Nerofe Formulation for treatment of adenocarcinoma in the anus with metastasis in the peritoneum

Using a new formulation of Nerofe on a patient (positive for ST2) with adenocarcinoma in the anus and two metastasis in the peritoneum caused the complete disappearance of tumors.

29 Nov|

ISK Ltd received FDA approval to start phase1/1b trial for treatment of GI tract mtKRAS tumors patients at Georgetown University at Washington DC23/10/2022

ISK Ltd received FDA approval to start phase1/1b trial for treatment of GI tract mtKRAS tumors patients at Georgetown University at Washington DC

23 Oct|

Phase II update – A second patient (92 years old) had a strong reduction in blasts in the bone marrow01/06/2022

No side effects were recorded

01 Jun|

Update from AML human trial in Miami04/05/2022

Who is entitled to enroll in the trial:
AML /Hi-Risk MDS patients with:

8 weeks of life expectancy.
clinically deteriorating.
have no more available treatments.

In cohort 1 (dose=6mg/m^2) three patients were enrolled.

The first patient was alive with this dose for 5 months.
The second patient was alive with this dose for 1.5 months.
The third

04 May|

Georgetown University at Washington DC has signed a contract with ISK to run a clinical trial with patients with mtKRAS tumors17/02/2022

The prestigious medical center Georgetown University at Washington DC has sign a contract with ISK to run a clinical trial with patients with mtKRAS pancreas and colon cancers.

17 Feb|

PHASE 1B/2A Clinical trial started13/04/2021

The Nerofe Phase 1B/2A trial with high risk MDS and AML patients is taking place at the University of Miami Sylvester Comprehensive Cancer Center.

13 Apr|

ISK received the FDA’s approval to start Phase 1b/2a with AML patients09/01/2020

09 Jan|