Nerofe causes ER stress to different type of cells

Nerofe causes ER stress to different type of cells

NEROFE® TRIPLE-ACTION:

In Vitro assays have shown that Nerofe causes ER stress to cancer and endothelial cells, thus leading to cancer cell death and depletion of angiogenesis factors from serum, as seen in Phase Ia results. Because Immune cells express ST2 (Nerofe’s receptor), it is hypothesized that a similar ER stress is caused by Nerofe and as documented causes an increase secretion of anti-cancer immune cytokines – as seen too in Phase Ia clinical trial results.

Thus fighting cancer from three different angles:

  •  Endothelial cells ER stress: causes Inhibition of angiogenesis.
  • Cancer cells ER stress: causes death of cancer cells.
  • Immune cells ER stress: Activates immune system response against cancer cells.